[Oxidative stress and lipid-protein peroxidation after cardiac transplantation. New hypotheses for explaining pathogenesis of accelerated forms of ischemic heart disease]
Résumé
The ischaemic heart disease developed by cardiac transplant patients is characterised by its rapid onset, which accounts for a number of its special features when compared with the usual form observed in non-immunosuppressed patients. However, the two forms of the disease are basically similar, that of the transplanted patients being practically a caricature of the non-immunosuppressed patients and thereby allowing a quasi-experimental model for the study of the metabolic causes of the disease which remains the leading cause of death in the world, all ages and sexes included, irrespective of the economic wealth of the countries.