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Article Dans Une Revue Theoretical Population Biology Année : 2007

The Genetical Bandwidth Mapping: A spatial and graphical representation of population genetic structure based on the Wombling method

Alain Cercueil
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Olivier Francois
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Résumé

Characterizing the spatial variation of allele frequencies in a population has a wide range of applications in population genetics. This article introduces a new nonparametric method, which provides a two-dimensional representation of a structural parameter called the genetical bandwidth, which describes genetic structure around arbitrary spatial locations in a study area. This parameter corresponds to the shortest distance to areas of significant allele variation, and its computation is based on the Womble's syslemic function. A simulation study and application to data sets taken from the literature give evidence that the method is particularly demonstrative when the fine-scale structure is stronger than the large-scale structure, and that it is generally able to locate genetic boundaries or clines precisely. (C) 2007 Elsevier Inc. All rights reserved.

Dates et versions

halsde-00283758 , version 1 (30-05-2008)

Identifiants

Citer

Alain Cercueil, Olivier Francois, S. Manel. The Genetical Bandwidth Mapping: A spatial and graphical representation of population genetic structure based on the Wombling method. Theoretical Population Biology, 2007, 71 (3), pp.332-341. ⟨10.1016/j.tpb.2007.01.007⟩. ⟨halsde-00283758⟩
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