MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue (Article De Synthèse) Peer Community Journal Année : 2023

MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes

Résumé

MacSyFinder is a program to model and detect macromolecular systems, genetic pathways… in protein datasets. In prokaryotes, these systems have often evolutionarily conserved properties: they are made of conserved components, they are encoded in compact loci (conserved genetic architecture). The user models these systems with MacSyFinder to reflect these conserved features, and to allow their efficient detection. Criteria for systems detection include component content (quorum), and genomic co-localization. Each component corresponds to a hidden Markov model (HMM) protein profile to perform sequence similarity searches with the program Hmmer.
Fichier principal
Vignette du fichier
10_24072_pcjournal_250.pdf (3.81 Mo) Télécharger le fichier
Licence : CC BY - Paternité

Dates et versions

pasteur-04060331 , version 1 (21-10-2022)
pasteur-04060331 , version 2 (06-04-2023)

Licence

Identifiants

Citer

Bertrand Néron, Rémi Denise, Charles Coluzzi, Marie Touchon, Eduardo P.C. Rocha, et al.. MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes. Peer Community Journal, 2023, 3, pp.e28. ⟨10.24072/pcjournal.250⟩. ⟨pasteur-04060331v2⟩
1819 Consultations
144 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More