Starting from one model, we check the possibility of using Berkeley-Madonna software to transpose and simulate some existing biological integrated models. The considered model is the one of Ikeda et al., proposed in 1979, which treats of fluid regulation and which is very well described mathematically in the original paper. Despite a few mistakes or bugs, the model has been easily and successfully implemented under Berkeley-Madonna. We recover the same simulation results as Ikeda and new simulations can now easily be carried out, thanks to the user-friendly qualities of Berkeley-Madonna.