Objective: In healthcare facilities, pressure injuries are a burden for medical staff since they not only result in longer care but also in increased risks of complications for the patients. Considering prevention, the aim is to hinder the propagation of the pressure ulcer and to speed up the healing time. Urgo RID recently developed a new bi-layer dressing to improve the healing of stage-2 and stage-3 heel pressure injuries. This study aims to numerically investigate the efficiency of this new bi-layer dressing to reduce strains around the pressure ulcer site. Methods: Three finite element models based on the same heel dataset were designed to compare the Green-Lagrange compressive and maximal shear strains in models without a pressure ulcer, with a stage-2 and with a stage-3 pressure ulcer. Simulations with and without the dressing were computed. Analysis of the results was performed in terms of strain clusters, defined as volumes of tissues with high shear and compressive strains. Results: The decrease of the peak and mean values of strains, between 0 % and 20 %, was small for the three models, but the reduction of the strain cluster volumes was important and up to 68 %. Conclusion: The cluster analysis enables the quantitative comparison of finite element analysis robustly. Results suggest that the use of the new bi-layer dressing may reduce the strains around the pressure ulcer sites and that it could also be used in a prophylactic manner. Results should be extended to a larger cohort of participants.